Download PDF by Tony Harris: Adherens Junctions: from Molecular Mechanisms to Tissue

By Tony Harris

Cell–cell adhesion is key for the improvement and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the simplest understood cell-cell adhesion complexes. during this quantity, a bunch of across the world famous specialists stories AJ biology over quite a lot of association; from atoms to molecules, to protein complexes, molecular networks, cells, tissues, and total animal improvement. AJs have additionally been a vital part of animal evolution, and play crucial roles in melanoma improvement, pathogen an infection and different ailments. This ebook addresses significant questions encompassing AJ biology.
• How did AJs evolve?
• How do cadherins and catenins have interaction to gather AJs and mediate adhesion?
• How do AJs interface with different mobile equipment to couple adhesion with the total telephone?
• How do AJs have an effect on mobilephone behaviour and multicellular improvement?
• How can irregular AJ task bring about disease?

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Adherens Junctions: from Molecular Mechanisms to Tissue Development and Disease: 60 (Subcellular Biochemistry) by Tony Harris


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